ABSTRACT
Objective:To explore the application effect of chewing gum combined with dexmedetomidine nasal drops in colonoscopy intestinal preparation and rapid rehabilitation.Methods:Using the method of clinical controlled trial and convenient sampling, 126 patients who underwent painless colonoscopy in Shaoxing Second Hospital from January 2019 to December 2020 were selected as the study subjects. The patients were divided into control group and observation group with 63 cases in each group by random number table method. The control group was prepared for routine colonoscopy, and the observation group was intervened with chewing gum on the basis of the operation method of the control group. The intestinal cleanliness, the effect of removing bubbles in the intestinal tract, the time consuming of colonoscopy operation (time consuming of inserting the colonoscope and time consuming of removing the colonoscope), defecation (time consuming of first defecation after operation, time consuming of stool emptying before operation) and adverse reactions during colonoscopy were compared between the two groups.Results:Before the intervention, there was no significant difference in the general data between the two groups ( P>0.05). After intervention, the cleanliness scores of the right colon, transverse colon and left colon in the observation group were (2.12 ± 0.58) points, (2.23 ± 0.75) points and (2.18 ± 0.46) points respectively, which were higher than those of the control group (1.82 ± 0.63) points, (1.93 ± 0.72) points and (1.90 ± 0.81) points, with a statistically significant difference ( t=-2.78, -2.29, -2.39, all P<0.05). The score of the effect of removing bubbles in the intestine in the observation group was (1.12 ± 0.41) points, it was lower than that of the control group (1.87 ± 0.45) points, and the difference was statistically significant ( t=9.78, P<0.05). After intervention, the time of inserting the mirror, the time of first defecation after operation and the time of emptying stool before operation in the observation group were (5.46 ± 1.12) min, (50.36 ± 10.67) min and (141.03 ± 14.31) min respectively, which were lower than those in the control group (6.53 ± 1.25) min, (67.02 ± 11.25) min and (153.35 ± 17.32) min, and the difference was statistically significant ( t=5.06, 8.53, 4.35, all P<0.05). There was no statistically significant difference between the two groups in the time of withdrawing the mirror ( P>0.05) and adverse reactions ( t=1.49, χ2=0.00, both P>0.05). Conclusions:Chewing gum combined with dexmedetomidine nasal drip can improve the effect of intestinal preparation and promote the rehabilitation after colonoscopy without increasing the risk of adverse reactions.